产品货号：
Z18498
中文名称：
HSD17B1抗体
英文名称：
Anti-HSD17B1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HSD17B1 Antibody |
| 指标别名 | 17 beta HSD 1;20 alpha HSD;E17KSR;E2DH;EDH17B1;EDH17B2;EDHB17;HSD17;HSD17B1;SDR28C1 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB |
| 基因名称 | HSD17B1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of rat HSD17B1(206-225aa ERADAQTRHLFAHYQRGYEQ),different from the related mouse sequence by one amino acid. |
| 实际分子量 | 37KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HSD17B1(17-BETA-HYDROXYSTEROID DEHYDROGENASE I),also known as 17-beta-hydroxysteroid dehydrogenase or 17-ketosteroid reductase,is an enzyme that is responsible for the interconversion of estrone(E1) and estradiol(E2) as well as the interconversion of androstenedione and testosterone.Its cytogenetic location is 17q21.2.HSD17B1 gene expression is detected in 34 of 42(81%) adenomas in all tumor subtypes;HSD17B2 mRNA is detected in 18 of 42(43%) adenomas but not in prolactinomas.Human estrogenic HSD17B1 is an NADP(H)-preferring enzyme.It possesses 11- and 4-fold higher specificity toward NADP(H) over NAD(H) for oxidation and reduction,respectively,as demonstrated by kinetic studies.All 4 HSD17B isoforms are variably expressed in human anterior pituitary adenomas,which also show HSD17B enzyme activity,suggesting that HSD17B may play an important role in regulating the local cellular levels of estradiol. |
| Uniprot ID | P51657 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | hydroxysteroid(17-beta) dehydrogenase 1 |
| 蛋白名全称 | Estradiol 17-beta-dehydrogenase 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：HSD17B1抗体，HSD17B1多抗，Anti-HSD17B1 Antibody